Frequently Asked Questions
Find answers to common questions about BiomarkerHelp, biomarker analysis, and how the platform works.
What is BiomarkerHelp?
BiomarkerHelp is a cancer biomarker analysis and clinical trial matching platform. Upload your NGS biomarker report, let our AI extract your mutations, and discover matched clinical trials and targeted therapies — all in one place.
What are cancer biomarkers?
Cancer biomarkers are specific genes, proteins, or other molecules that can influence how cancer grows and responds to treatment. Common examples include BRAF, KRAS, EGFR, ALK, and HER2 mutations. Biomarker testing (often through NGS) helps oncologists identify which treatments may be most effective for your specific cancer.
What is NGS testing?
NGS (Next Generation Sequencing) is a comprehensive genomic test that analyzes your tumor DNA to identify actionable mutations, fusions, amplifications, and other biomarkers. Labs like Foundation Medicine, Guardant Health, Caris Life Sciences, and Tempus perform these tests. Your oncologist may order NGS testing to help guide treatment decisions.
How does biomarker matching work?
After you upload your biomarker report, our AI extracts the relevant mutations and biomarkers. We then search ClinicalTrials.gov for actively recruiting trials that target your specific biomarkers, and match them against our curated database of FDA-approved targeted therapies. This gives you a personalized view of both trial opportunities and approved treatments.
Which lab reports are supported?
BiomarkerHelp supports PDF reports from major NGS labs including Foundation Medicine (FoundationOne CDx), Guardant Health (Guardant360), Caris Life Sciences (MI Profile), and Tempus (xT/xF). Our AI is designed to read and extract biomarker data from a variety of report formats. If your report format is not recognized, you can always add biomarkers manually.
What cancer types are covered?
BiomarkerHelp covers 47 cancer types including lung, breast, colorectal, melanoma (skin), prostate, ovarian, pancreatic, bladder, and many more. Our trial search draws from all cancer-related studies on ClinicalTrials.gov, and our drug matching database covers major actionable biomarker-drug pairs across solid tumors and hematologic cancers.
How does AI extraction work?
When you upload a PDF biomarker report, our AI reads the document and identifies gene mutations (e.g., BRAF V600E), fusions (e.g., ALK-EML4), amplifications (e.g., HER2), and status markers (e.g., MSI-High, TMB-High, PD-L1). The extracted biomarkers are added to your profile automatically. You can review, edit, or add to them at any time.
What about drug matching?
Our drug matching feature compares your biomarkers against a curated database of FDA-approved targeted therapies and immunotherapies. For example, if you have a BRAF V600E mutation, you will see matched drugs like vemurafenib and dabrafenib + trametinib. This is informational only — always discuss treatment options with your oncologist.
Is BiomarkerHelp free?
Yes, BiomarkerHelp is 100% free. There are no subscription fees, hidden charges, or premium tiers. We believe that access to biomarker analysis and clinical trial information should be available to every cancer patient at no cost.
Is my data secure?
Absolutely. We take data security seriously, especially for genetic and biomarker data. BiomarkerHelp implements industry-standard encryption for data in transit and at rest, follows HIPAA-compliant practices, and maintains strict access controls. Your genetic data is protected under the Genetic Information Nondiscrimination Act (GINA) and is never shared with employers or insurers. You can review our full Privacy Policy and HIPAA Notice for details.
How do I contact support?
You can reach our support team by emailing [email protected]. We aim to respond to all inquiries within one business day.